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4-Fluorobutyrfentanyl
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    4-Fluorobutyrfentanyl

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    4-Fluorobutyrfentanyl
    4-Fluorobutyrfentanyl.svg
    P-fluorobutryrylfentanyl 3D BS.png
    Legal status
    Legal status
    Identifiers
    • N-(4-Fluorophenyl)-N-[1-(2-phenylethyl)-4-piperidinyl]-butanamide
    CAS Number
    PubChem CID
    ChemSpider
    UNII
    Chemical and physical data
    Formula C23H29FN2O
    Molar mass 368.496 g·mol−1
    3D model (JSmol)
    • CCCC(=O)N(C1CCN(CC1)CCC2=CC=CC=C2)C3=CC=C(C=C3)F
    • InChI=1S/C23H29FN2O/c1-2-6-23(27)26(21-11-9-20(24)10-12-21)22-14-17-25(18-15-22)16-13-19-7-4-3-5-8-19/h3-5,7-12,22H,2,6,13-18H2,1H3
    • Key:QZFMCYUBPSLOBP-UHFFFAOYSA-N

    4-Fluorobutyrylfentanyl (also known as 4-FBF and p-FBF or para-fluorobutyrylfentanyl) is an opioid analgesic that is an analog of butyrfentanyl and has been sold online as a designer drug. It is closely related to 4-fluorofentanyl, which has an EC50 value of 4.2 nM for the human μ-opioid receptor.

    Side effects

    Side effects of fentanyl analogs are similar to those of fentanyl itself, which include itching, nausea and potentially serious respiratory depression, which can be life-threatening. Fentanyl analogs have killed hundreds of people throughout Europe and the former Soviet republics since the most recent resurgence in use began in Estonia in the early 2000s, and novel derivatives continue to appear.

    Legal status

    Sweden's public health agency suggested classifying 4-fluorobutyrylfentanyl as hazardous substance on August 18, 2014.

    In October 2015, 4-fluorobutyrylfentanyl became a controlled substance in China.

    4-Fluorobutyrfentanyl is a Schedule I controlled drug in the USA since 1. February 2018.

    See also


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