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Abandoned drugs
Dihydrotestosterone undecanoate
Другие языки:

    Dihydrotestosterone undecanoate

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    Dihydrotestosterone undecanoate
    Dihydrotestosterone undecanoate.svg
    Clinical data
    Other names DHTU; 5α-Dihydrotestosterone 17β-undecanoate; Androstanolone undecanoate; Stanolone undecanoate; 5α-Androstan-17β-ol-3-one 17β-undecanoate; 3-Oxo-5α-androstan-17β-yl undecanoate
    Routes of
    administration    		 By mouth
    Drug class Androgen; Anabolic steroid; Androgen ester
    Identifiers
    • [(5S,8R,9S,10S,13S,14S,17S)-10,13-Dimethyl-3-oxo-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl] undecanoate
    CAS Number
    PubChem CID
    ChemSpider
    UNII
    CompTox Dashboard (EPA)
    Chemical and physical data
    Formula C30H50O3
    Molar mass 458.727 g·mol−1
    3D model (JSmol)
    • CCCCCCCCCCC(=O)O[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC[C@@H]4[C@@]3(CCC(=O)C4)C)C
    • InChI=1S/C30H50O3/c1-4-5-6-7-8-9-10-11-12-28(32)33-27-16-15-25-24-14-13-22-21-23(31)17-19-29(22,2)26(24)18-20-30(25,27)3/h22,24-27H,4-21H2,1-3H3/t22-,24-,25-,26-,27-,29-,30-/m0/s1
    • Key:AOQIVBOEDICQDB-KNWHVVHCSA-N

    Dihydrotestosterone undecanoate (DHTU), also known as androstanolone undecanoate or stanolone undecanoate, is a synthetic androgen and anabolic steroid (AAS) which was never marketed. It is an androgen ester; specifically, it is the C17β undecanoate (undecylate) ester of dihydrotestosterone (DHT). DHTU is a prodrug of DHT. Similarly to testosterone undecanoate (TU), DHTU is orally active. It occurs as an important active metabolite of oral TU. The 5α-reductase inhibitor finasteride in combination with oral TU has no effect on the first-pass transformation of TU into DHTU or DHT, probably because of its unique lymphatic route of absorption. Oral DHTU may be absorbed by the lymphatic system similarly to TU, and this may explain its oral bioavailability.

    See also



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