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Combined estrogen–progestogen formulations
Estradiol/norethisterone acetate
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    Estradiol/norethisterone acetate

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    Estradiol/norethisterone acetate
    Combination of
    Estradiol Estrogen
    Norethisterone acetate Progestogen
    Clinical data
    Trade names Activella, Amabelz, CombiPatch, others
    AHFS/Drugs.com Professional Drug Facts
    MedlinePlus a601041
    Routes of
    administration    		 By mouth
    ATC code
    Legal status
    Legal status
    Identifiers
    CAS Number
    ChemSpider
    • none
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    Estradiol/norethisterone acetate (E2/NETA), sold under the brand name Activella among others, is a combination of estradiol (E2) and norethisterone acetate (NETA) which is used in the treatment of vasomotor symptoms, vulvar and vaginal atrophy, and osteoporosis associated with menopause. Activella specifically is marketed by Novo Nordisk and is supplied as film-coated tablets containing 1 mg estradiol and 0.5 mg norethisterone acetate. CombiPatch is a combination of estradiol and NETA provided as a transdermal patch.

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