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Antidepressant
Hydroxynefazodone
Другие языки:

Hydroxynefazodone

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Hydroxynefazodone
Hydroxynefazodone.svg
Clinical data
Other names OH-NEF
Pharmacokinetic data
Elimination half-life 1.5–4 hours
Identifiers
  • 2-[3-[4-(3-Chlorophenyl)piperazin-1-yl]propyl]-5-(1-hydroxyethyl)-4-(2-phenoxyethyl)-1,2,4-triazol-3-one
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
Formula C25H32ClN5O3
Molar mass 486.01 g·mol−1
3D model (JSmol)
  • CC(C1=NN(C(=O)N1CCOC2=CC=CC=C2)CCCN3CCN(CC3)C4=CC(=CC=C4)Cl)O
  • InChI=1S/C25H32ClN5O3/c1-20(32)24-27-31(25(33)30(24)17-18-34-23-9-3-2-4-10-23)12-6-11-28-13-15-29(16-14-28)22-8-5-7-21(26)19-22/h2-5,7-10,19-20,32H,6,11-18H2,1H3
  • Key:VKGQYGXMUUBRBD-UHFFFAOYSA-N

Hydroxynefazodone is a phenylpiperazine compound and a major metabolite of the antidepressant nefazodone. It has similar biological activity and a similar elimination half-life (1.5 to 4 hours) to those of nefazodone, and may contribute significantly to its effects.

See also




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