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Mu-opioid receptor agonists
M320 (opioid)
Другие языки:

    M320 (opioid)

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    M320 (opioid)
    Isopentyl orvinol M320.svg
    Clinical data
    Other names (5α,6β,14β,18R)-17-(Cyclopropylmethyl)-18-[(2R)-2-hydroxy-5-methyl-2-hexanyl]-6-methoxy-7,8-didehydro-18,19-dihydro-4,5-epoxy-6,14-ethenomorphinan-3-ol
    ATC code
    • none
    Legal status
    Legal status
    Identifiers
    • (1R,2S,6R,14R,15R,19R)-5-(Cyclopropylmethyl)-19-[(2R)-2-hydroxy-5-methylhexan-2-yl]-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11,16-tetraen-11-ol
    PubChem CID
    ChemSpider
    ChEMBL
    Chemical and physical data
    Formula C30H41NO4
    Molar mass 479.661 g·mol−1
    3D model (JSmol)
    • CC(C)CC[C@](C)([C@H]1C[C@@]23C=C[C@@]1([C@H]4[C@@]25CCN([C@@H]3CC6=C5C(=C(C=C6)O)O4)CC7CC7)OC)O
    • InChI=1S/C30H41NO4/c1-18(2)9-10-27(3,33)22-16-28-11-12-30(22,34-4)26-29(28)13-14-31(17-19-5-6-19)23(28)15-20-7-8-21(32)25(35-26)24(20)29/h7-8,11-12,18-19,22-23,26,32-33H,5-6,9-10,13-17H2,1-4H3/t22-,23-,26-,27-,28-,29+,30-/m1/s1
    • Key:MFIWLPVODKSMKX-XELDOGJXSA-N

    M320 is an extremely potent and long acting opioid. It produces long lasting narcosis in different animals, including mice, rats, cats, guinea pigs, dogs and monkeys. M320 is a μ and κ-opioid receptor agonist.

    See also



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