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Mu-opioid receptor agonists
Methylketobemidone
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    Methylketobemidone

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    Methylketobemidone
    Methylketobemidone.svg
    Clinical data
    ATC code
    • none
    Identifiers
    • 1-[4-(3-hydroxyphenyl)-1-methylpiperidin-4-yl]ethanone
    CAS Number
    PubChem CID
    ChemSpider
    UNII
    CompTox Dashboard (EPA)
    Chemical and physical data
    Formula C14H19NO2
    Molar mass 233.311 g·mol−1
    3D model (JSmol)
    • O=C(C2(c1cccc(O)c1)CCN(C)CC2)C
    • InChI=1S/C14H19NO2/c1-11(16)14(6-8-15(2)9-7-14)12-4-3-5-13(17)10-12/h3-5,10,17H,6-9H2,1-2H3 checkY
    • Key:RNAGZQQIHXIDQH-UHFFFAOYSA-N checkY
      (verify)

    Methylketobemidone is an opioid analgesic that is an analogue of ketobemidone. It was developed in the 1950s during research into analogues of pethidine and was assessed by the United Nations Office on Drugs and Crime but was not included on the list of drugs under international control, probably because it was not used in medicine or widely available.

    Methylketobemidone is so named because it is the methyl ketone analogue of bemidone (hydroxypethidine). The more commonly used ethyl ketone ("ethylketobemidone") is simply called ketobemidone, as it is the only drug of this family to have been marketed.

    Presumably methylketobemidone produces similar effects to ketobemidone and other opioids, such as analgesia and sedation, along with side effects such as nausea, itching, vomiting and respiratory depression which may be harmful or fatal.



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