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Abandoned drugs
Metonitazene
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    Metonitazene

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    Metonitazene
    Metonitazene.svg
    Legal status
    Legal status
    Identifiers
    • 2-[2-(4-Methoxybenzyl)-5-nitro-1H-benzimidazol-1-yl]-N,N-diethylethanamine
    CAS Number
    PubChem CID
    ChemSpider
    UNII
    Chemical and physical data
    Formula C21H26N4O3
    Molar mass 382.464 g·mol−1
    3D model (JSmol)
    • CCN(CC)CCN1C2=C(C=C(C=C2)[N+](=O)[O-])N=C1CC3=CC=C(C=C3)OC
    • InChI=1S/C21H26N4O3/c1-4-23(5-2)12-13-24-20-11-8-17(25(26)27)15-19(20)22-21(24)14-16-6-9-18(28-3)10-7-16/h6-11,15H,4-5,12-14H2,1-3H3
    • Key:HNGZTLMRQTVPBH-UHFFFAOYSA-N

    Metonitazene is an analgesic compound related to etonitazene, which was first reported in 1957, and has been shown to have approximately 100 times the potency of morphine by central routes of administration, but if used orally it has been shown to have approximately 10 times the potency of morphine.

    Its effects are similar to other opioids such as fentanyl and heroin, including analgesia, euphoria, and sleepiness. Adverse effects include vomiting, and respiratory depression that can potentially be fatal. Because of high dependency potential and dangerous adverse effects it has never been introduced into pharmacotherapy.

    Legal status

    In the United States, metonitazene is a Schedule I controlled substance under the Controlled Substances Act.

    Metonitazene is not controlled under the 1971 Convention on Psychotropic Substances; however, in many countries possession or intent to sell for human consumption might be prosecuted under several analog acts.

    See also


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