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Abandoned drugs
Niravoline
Другие языки:

    Niravoline

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    Niravoline
    Niravoline.svg
    Names
    Preferred IUPAC name
    N-Methyl-2-(3-nitrophenyl)-N-[(1S,2S)-2-(pyrrolidin-1-yl)-2,3-dihydro-1H-inden-1-yl]acetamide
    Identifiers
    3D model (JSmol)
    PubChem CID
    UNII
    • InChI=1S/C22H25N3O3/c1-23(21(26)14-16-7-6-9-18(13-16)25(27)28)22-19-10-3-2-8-17(19)15-20(22)24-11-4-5-12-24/h2-3,6-10,13,20,22H,4-5,11-12,14-15H2,1H3/t20-,22-/m0/s1
      Key: ZSDAQBWGAOKTSI-UNMCSNQZSA-N
    • CN([C@@H]1[C@H](CC2=CC=CC=C12)N3CCCC3)C(=O)CC4=CC(=CC=C4)[N+](=O)[O-]
    Properties
    C22H25N3O3
    Molar mass 379.460 g·mol−1
    Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

    Niravoline is a chemical compound with the formula C
    22    H
    25    N
    3    O
    3    . It has diuretic and aquaretic effects and has been studied for its potential use for cerebral edema and cirrhosis.

    It exerts its pharmacological effect as a kappa opioid receptor agonist.




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