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Prazitone
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Clinical data | |
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Other names | 5-phenyl-5-(2-piperidylmethyl)barbituric acid |
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Chemical and physical data | |
Formula | C16H19N3O3 |
Molar mass | 301.346 g·mol−1 |
3D model (JSmol) | |
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NY (what is this?) (verify) |
Prazitone (AGN-511) is a barbiturate derivative developed in the 1970s. Unlike most barbiturates, it has little or no sedative effects, instead acting as a non-sedating anxiolytic and antidepressant. The dosage range in humans is around 200–600 mg, although higher doses have been used in trials for the treatment of depression associated with Parkinson's disease.
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5-HT1AR agonists | |
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GABAAR PAMs |
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Gabapentinoids |
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Antidepressants |
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Sympatholytics |
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Others | |
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Alcohols | |
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Barbiturates |
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Benzodiazepines |
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Carbamates | |
Flavonoids |
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Imidazoles | |
Kava constituents | |
Monoureides | |
Neuroactive steroids |
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Nonbenzodiazepines | |
Phenols | |
Piperidinediones | |
Pyrazolopyridines | |
Quinazolinones | |
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Others/unsorted |
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Simple piperazines (no additional rings) |
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Phenylpiperazines |
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Benzylpiperazines | |
Diphenylalkylpiperazines (benzhydrylalkylpiperazines) |
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Pyrimidinylpiperazines | |
Pyridinylpiperazines | |
Benzo(iso)thiazolylpiperazines | |
Tricyclics (piperazine attached via side chain) |
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Others/Uncategorized |