Zinc finger protein 180

ZNF180
Identifiers
Aliases	ZNF180, HHZ168, zinc finger protein 180
External IDs	OMIM: 606740 MGI: 1923701 HomoloGene: 8306 GeneCards: ZNF180
Gene location (Human) Chr. Chromosome 19 (human) Band 19q13.31 Start 44,474,428 bp End 44,500,524 bp
Gene location (Mouse) Chr. Chromosome 7 (mouse) Band 7|7 A3 Start 23,781,349 bp End 23,807,138 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in endothelial cell Achilles tendon ganglionic eminence islet of Langerhans sural nerve parietal pleura monocyte stromal cell of endometrium rectum Left adrenal gland Top expressed in hand olfactory tubercle superior cervical ganglion primary motor cortex Region I of hippocampus proper superior frontal gyrus nucleus accumbens cingulate gyrus globus pallidus otolith organ More reference expression data BioGPS n/a
Gene ontology Molecular function DNA binding protein binding metal ion binding nucleic acid binding DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component intracellular anatomical structure nucleus Biological process regulation of transcription, DNA-templated transcription, DNA-templated regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 7733 210135 Ensembl ENSG00000167384 ENSMUSG00000057101 UniProt Q9UJW8 n/a RefSeq (mRNA) NM_001278508 NM_001278509 NM_001288759 NM_001288760 NM_001288761 NM_001288762 NM_001291633 NM_013256 NM_001045486 NM_001289634 NM_001289637 NM_001289640 NM_001289641 NM_172483 RefSeq (protein) NP_001265437 NP_001265438 NP_001275688 NP_001275689 NP_001275690 NP_001275691 NP_001278562 NP_037388 n/a Location (UCSC) Chr 19: 44.47 – 44.5 Mb Chr 7: 23.78 – 23.81 Mb PubMed search
Wikidata
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Zinc finger protein 180 is a protein that is encoded in humans by the ZNF180 gene.

Function

Zinc finger proteins have been shown to interact with nucleic acids and to have diverse functions. The zinc finger domain is a conserved amino acid sequence motif containing two specifically positioned cysteines and two histidines that are involved in coordinating zinc. Kruppel-related proteins form one family of zinc finger proteins. See MIM 604749 for additional information on zinc finger proteins.

External links

• This article incorporates text from the United States National Library of Medicine, which is in the public domain.