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Mu-opioid receptor agonists
Acetoxyketobemidone
Другие языки:

    Acetoxyketobemidone

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    Acetoxyketobemidone
    Acetoxyketobemidone.svg
    Clinical data
    Other names Acetoxyketobemidone, O-Acetylketobemidone
    ATC code
    • none
    Identifiers
    • 1-[4-(3-acetoxyphenyl)-1-methylpiperidin-4-yl]propan-1-one
    CAS Number
    ChemSpider
    UNII
    CompTox Dashboard (EPA)
    Chemical and physical data
    Formula C17H23NO3
    Molar mass 289.38 g·mol−1
    3D model (JSmol)
    • O=C(CC)C1(CCN(C)CC1)c2cccc(OC(C)=O)c2
    • InChI=1S/C17H23NO3/c1-4-16(20)17(8-10-18(3)11-9-17)14-6-5-7-15(12-14)21-13(2)19/h5-7,12H,4,8-11H2,1-3H3 checkY
    • Key:UHZAKWBTNFQWFQ-UHFFFAOYSA-N checkY
      (verify)

    Acetoxyketobemidone (O-Acetylketobemidone) is an opioid analgesic that is an acetylated derivative of ketobemidone. It was developed in the 1950s during research into analogues of pethidine and was assessed by the United Nations Office on Drugs and Crime but was not included on the list of drugs under international control, probably because it was not used in medicine or widely available. Nevertheless, acetoxyketobemidone is controlled as an ester of ketobemidone, which is included in Schedule I of the Single Convention on Narcotic Drugs of 1961.

    Presumably acetoxyketobemidone produces similar effects to ketobemidone and other opioids, such as analgesia and sedation, along with side effects such as nausea, itching, vomiting and respiratory depression which may be harmful or fatal.




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