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Mu-opioid receptor agonists
Alphamethylthiofentanyl
Другие языки:

Alphamethylthiofentanyl

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Alphamethylthiofentanyl
Alphamethylthiofentanyl.svg
Clinical data
Other names α-methyl-thiofentanyl
ATC code
  • none
Legal status
Legal status
Identifiers
  • N-Phenyl-N-[1-(1-thiophen-2-ylpropan-2-yl)-4-piperidyl]propanamide
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
Chemical and physical data
Formula C21H28N2OS
Molar mass 356.53 g·mol−1
3D model (JSmol)
  • O=C(N(c1ccccc1)C2CCN(CC2)C(Cc3sccc3)C)CC
  • InChI=1S/C21H28N2OS/c1-3-21(24)23(18-8-5-4-6-9-18)19-11-13-22(14-12-19)17(2)16-20-10-7-15-25-20/h4-10,15,17,19H,3,11-14,16H2,1-2H3 checkY
  • Key:YPOXDUYRRSUFFG-UHFFFAOYSA-N checkY
  (verify)

α-methyl-thiofentanyl is an opioid analgesic that is an analogue of fentanyl.

α-methyl-thiofentanyl was sold briefly on the black market in the early 1980s, before the introduction of the Federal Analog Act which for the first time attempted to control entire families of drugs based on their structural similarity rather than scheduling each drug individually as they appeared.

α-methyl-thiofentanyl has similar effects to fentanyl. Side effects of fentanyl analogs are similar to those of fentanyl itself, which include itching, nausea and potentially serious respiratory depression, which can be life-threatening. Fentanyl analogs have killed hundreds of people throughout Europe and the former Soviet republics since the most recent resurgence in use began in Estonia in the early 2000s, and novel derivatives continue to appear.


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