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Abandoned drugs
Axomadol
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    Axomadol

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    Axomadol
    Axomadol Structure.svg
    Clinical data
    ATC code
    • None
    Legal status
    Legal status
    Identifiers
    • (1R,3R,6R)-6-[(dimethylamino)methyl]-1-(3-methoxyphenyl)-1,3-cyclohexanediol
    CAS Number
    PubChem CID
    ChemSpider
    UNII
    CompTox Dashboard (EPA)
    Chemical and physical data
    Formula C16H25NO3
    Molar mass 279.380 g·mol−1
    3D model (JSmol)
    • O[C@]2(c1cc(OC)ccc1)C[C@H](O)CC[C@@H]2CN(C)C
    • InChI=1S/C16H25NO3/c1-17(2)11-13-7-8-14(18)10-16(13,19)12-5-4-6-15(9-12)20-3/h4-6,9,13-14,18-19H,7-8,10-11H2,1-3H3/t13-,14-,16+/m1/s1
    • Key:LQJLLAOISDVBJM-FMKPAKJESA-N

    Axomadol (INN, USAN) (code name EN3324) is a synthetic, centrally-acting opioid analgesic of the benzenoid class which was under investigation by Endo Pharmaceuticals in collaboration with Grünenthal for the treatment of chronic, moderate to severe lower back pain and arthrosis. Development was halted after phase II clinical trials as it did not meet the pre-determined clinical endpoints.

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