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Mu-opioid receptor agonists
BDPC
Другие языки:

    BDPC

    Подписчиков: 0, рейтинг: 0
    Not to be confused with bromperidol or bromadoline.
    BDPC
    Bromadol.svg
    Bromadol 3D BS.png
    Clinical data
    ATC code
    • None
    Identifiers
    • 4-(4-Bromophenyl)-4-(dimethylamino)-1-(2-phenylethyl)cyclohexan-1-ol
    CAS Number
    PubChem CID
    ChemSpider
    UNII
    ChEMBL
    Chemical and physical data
    Formula C22H28BrNO
    Molar mass 402.376 g·mol−1
    3D model (JSmol)
    Melting point 208 to 210 °C (406 to 410 °F)
    • CN(C)C1(CCC(CC1)(CCC2=CC=CC=C2)O)C3=CC=C(C=C3)Br
    • InChI=1S/C22H28BrNO/c1-24(2)22(19-8-10-20(23)11-9-19)16-14-21(25,15-17-22)13-12-18-6-4-3-5-7-18/h3-11,25H,12-17H2,1-2H3 checkY
    • Key:PRSUTWWKYIVBEU-UHFFFAOYSA-N checkY
      (verify)

    BDPC (systematic name 4-(4-bromophenyl)-4-(dimethylamino)-1-(2-phenylethyl)cyclohexanol; also known as bromadol) is a potent narcotic analgesic with a distinctive arylcyclohexylamine chemical structure. It was developed by Daniel Lednicer at Upjohn in the 1970s. Initial studies estimated that it was around 10,000 times the strength of morphine in animal models. However, later studies using more modern techniques assigned a value of 504 times the potency of morphine for the more active trans-isomer. This drug was first seized along with three kilograms of acetylfentanyl in an April 25, 2013 police action in Montreal, Canada, and has reportedly continued to be available on the designer drug black market internationally. Analogues where the para-bromine is replaced by chlorine or a methyl group retain similar activity, as does the meta-hydroxyl derivative.

    p-methyl analogue of BDPC
    p-chloro analogue of BDPC. [1]
    m-hydroxy analogue of BDPC. [2]

    See also


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