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Abandoned drugs
Cyanonilutamide
Другие языки:

    Cyanonilutamide

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    Cyanonilutamide
    Cyanonilutamide.svg
    Clinical data
    Other names RU-56279
    Drug class Nonsteroidal antiandrogen
    Identifiers
    • 4-(4,4-Dimethyl-2,5-dioxoimidazolidin-1-yl)-2-(trifluoromethyl)benzonitrile
    CAS Number
    PubChem CID
    ChemSpider
    UNII
    ChEMBL
    Chemical and physical data
    Formula C13H10F3N3O2
    Molar mass 297.237 g·mol−1
    3D model (JSmol)
    • CC1(C(=O)N(C(=O)N1)C2=CC(=C(C=C2)C#N)C(F)(F)F)C
    • InChI=1S/C13H10F3N3O2/c1-12(2)10(20)19(11(21)18-12)8-4-3-7(6-17)9(5-8)13(14,15)16/h3-5H,1-2H3,(H,18,21)
    • Key:CYCKLVAQENOQPG-UHFFFAOYSA-N

    Cyanonilutamide (developmental code name RU-56279) is a nonsteroidal antiandrogen which was never marketed. Both RU-56187 and RU-58841 appear to be prodrugs of cyanonilutamide in vivo in animals. It has relatively low affinity for the androgen receptor but nonetheless shows significant antiandrogenic activity in animals.

    See also



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