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Cyclopropylfentanyl
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    Cyclopropylfentanyl

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    Cyclopropylfentanyl
    Cyclopropylfentanyl.svg
    Cyclopropylfentanyl 3D BS.png
    Legal status
    Legal status
    Identifiers
    • N-Phenyl-N-[1-(2-Phenylethyl)piperidin-4-yl]cyclopropanecarboxamide
    CAS Number
    PubChem CID
    ChemSpider
    UNII
    Chemical and physical data
    Formula C23H28N2O
    Molar mass 348.490 g·mol−1
    3D model (JSmol)
    • C1CC1C(=O)N(C2CCN(CC2)CCC3=CC=CC=C3)C4=CC=CC=C4
    • InChI=1S/C23H28N2O/c26-23(20-11-12-20)25(21-9-5-2-6-10-21)22-14-17-24(18-15-22)16-13-19-7-3-1-4-8-19/h1-10,20,22H,11-18H2
    • Key:OIQSKDSKROTEMN-UHFFFAOYSA-N

    Cyclopropylfentanyl is an opioid analgesic that is an analog of fentanyl and has been sold as a designer drug. Between June and December 2017, a total of 78 cyclopropylfentanyl-related deaths with analytical confirmation in post-mortem samples were reported by various European countries. Another 115 deaths involving cyclopropylfentanyl were reported from the United States in 2017.

    Side effects

    Side effects of fentanyl analogs are similar to those of fentanyl itself, which include itching, nausea and potentially serious respiratory depression, which can be life-threatening. Fentanyl analogs have killed hundreds of people throughout Europe and the former Soviet republics since the most recent resurgence in use began in Estonia in the early 2000s, and novel derivatives continue to appear. A new wave of fentanyl analogues and associated deaths began in around 2014 in the US, and have continued to grow in prevalence; especially since 2016 these drugs have been responsible for hundreds of overdose deaths every week.

    Legal status

    Cyclopropylfentanyl was banned in Finland in September 2017, and in Sweden in October 2017. It is a Schedule I controlled drug in the USA since January 2018. In September 2018 the European Union subjected cyclopropylfentanyl to control measures.

    See also


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