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| Clinical data | |
|---|---|
| Trade names | Faragynol, Gynocyrol |
| Other names | Dienestrol acetate; Lipamone |
| Drug class | Nonsteroidal estrogen; Estrogen ester |
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| ChEMBL | |
| CompTox Dashboard (EPA) | |
| Chemical and physical data | |
| Formula | C22H22O4 |
| Molar mass | 350.414 g·mol−1 |
| 3D model (JSmol) | |
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Dienestrol diacetate (brand names Faragynol, Gynocyrol, others) is a synthetic nonsteroidal estrogen of the stilbestrol group related to diethylstilbestrol. It is an ester of dienestrol.
| Compound | Dosage for specific uses (mg usually) | ||||||
|---|---|---|---|---|---|---|---|
| ETD | EPD | MSD | MSD | OID | TSD | ||
| Estradiol (non-micron.) | 30 | ≥120–300 | 120 | 6 | - | - | |
| Estradiol (micronized) | 6–12 | 60–80 | 14–42 | 1–2 | >5 | >8 | |
| Estradiol valerate | 6–12 | 60–80 | 14–42 | 1–2 | - | >8 | |
| Estradiol benzoate | - | 60–140 | - | - | - | - | |
| Estriol | ≥20 | 120–150 | 28–126 | 1–6 | >5 | - | |
| Estriol succinate | - | 140–150 | 28–126 | 2–6 | - | - | |
| Estrone sulfate | 12 | 60 | 42 | 2 | - | - | |
| Conjugated estrogens | 5–12 | 60–80 | 8.4–25 | 0.625–1.25 | >3.75 | 7.5 | |
| Ethinylestradiol | 200 μg | 1–2 | 280 μg | 20–40 μg | 100 μg | 100 μg | |
| Mestranol | 300 μg | 1.5–3.0 | 300–600 μg | 25–30 μg | >80 μg | - | |
| Quinestrol | 300 μg | 2–4 | 500 μg | 25–50 μg | - | - | |
| Methylestradiol | - | 2 | - | - | - | - | |
| Diethylstilbestrol | 2.5 | 20–30 | 11 | 0.5–2.0 | >5 | 3 | |
| DES dipropionate | - | 15–30 | - | - | - | - | |
| Dienestrol | 5 | 30–40 | 42 | 0.5–4.0 | - | - | |
| Dienestrol diacetate | 3–5 | 30–60 | - | - | - | - | |
| Hexestrol | - | 70–110 | - | - | - | - | |
| Chlorotrianisene | - | >100 | - | - | >48 | - | |
| Methallenestril | - | 400 | - | - | - | - | |
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Sources and footnotes:
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| Estrogen | Form | Major brand name(s) | EPD (14 days) | Duration | |
|---|---|---|---|---|---|
| Diethylstilbestrol (DES) | Oil solution | Metestrol | 20 mg | 1 mg ≈ 2–3 days; 3 mg ≈ 3 days | |
| Diethylstilbestrol dipropionate | Oil solution | Cyren B | 12.5–15 mg | 2.5 mg ≈ 5 days | |
| Aqueous suspension | ? | 5 mg | ? mg = 21–28 days | ||
| Dimestrol (DES dimethyl ether) | Oil solution | Depot-Cyren, Depot-Oestromon, Retalon Retard | 20–40 mg | ? | |
| Fosfestrol (DES diphosphate)a | Aqueous solution | Honvan | ? | <1 day | |
| Dienestrol diacetate | Aqueous suspension | Farmacyrol-Kristallsuspension | 50 mg | ? | |
| Hexestrol dipropionate | Oil solution | Hormoestrol, Retalon Oleosum | 25 mg | ? | |
| Hexestrol diphosphatea | Aqueous solution | Cytostesin, Pharmestrin, Retalon Aquosum | ? | Very short | |
| Note: All by intramuscular injection unless otherwise noted. Footnotes: a = By intravenous injection. Sources: See template. | |||||