Мы используем файлы cookie.
Продолжая использовать сайт, вы даете свое согласие на работу с этими файлами.
Abandoned drugs
Diethylstilbestrol dipalmitate
Другие языки:

    Diethylstilbestrol dipalmitate

    Подписчиков: 0, рейтинг: 0
    Diethylstilbestrol dipalmitate
    Diethylstilbestrol dipalmitate.svg
    Clinical data
    Trade names Palmestril, Stilpalmitate
    Other names Stilpalmitate
    Routes of
    administration    		 Intramuscular injection
    Identifiers
    • [4-[(E)-4-(4-Hexadecanoyloxyphenyl)hex-3-en-3-yl]phenyl] hexadecanoate
    CAS Number
    PubChem CID
    ChemSpider
    UNII
    CompTox Dashboard (EPA)
    Chemical and physical data
    Formula C50H80O4
    Molar mass 745.186 g·mol−1
    3D model (JSmol)
    • CCCCCCCCCCCCCCCC(=O)OC1=CC=C(C=C1)/C(=C(\CC)/C2=CC=C(C=C2)OC(=O)CCCCCCCCCCCCCCC)/CC
    • InChI=1S/C50H80O4/c1-5-9-11-13-15-17-19-21-23-25-27-29-31-33-49(51)53-45-39-35-43(36-40-45)47(7-3)48(8-4)44-37-41-46(42-38-44)54-50(52)34-32-30-28-26-24-22-20-18-16-14-12-10-6-2/h35-42H,5-34H2,1-4H3/b48-47+
    • Key:JUHYOIKJCUMOSQ-QJGAVIKSSA-N

    Diethylstilbestrol dipalmitate (brand names Palmestril, Stilpalmitate), also known as stilpalmitate, is a synthetic, nonsteroidal estrogen of the stilbestrol group and an ester of diethylstilbestrol (DES) that was formerly marketed but is now no longer available. Its actions and uses are essentially the same as those of DES, but it is absorbed more slowly and for this reason has a much longer duration of action and improved tolerability in comparison. A single 5 mg intramuscular injection of DES dipalmitate in oil solution has been found to have an average duration of action of 8 to 10 weeks in terms of relief of menopausal symptoms, with a duration of as long as 15 to 16 weeks occurring in some women. A single 15 or 20 mg intramuscular injection of DES dipalmitate in oil solution will control menopausal symptoms for 3 months or longer. DES dipalmitate in aqueous suspension by intramuscular injection has been studied as well.

    See also



    Новое сообщение