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Abandoned drugs
Dimethandrolone buciclate
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    Dimethandrolone buciclate

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    Dimethandrolone buciclate
    Dimethandrolone buciclate.svg
    Clinical data
    Other names CDB-4386A; 7α,11β-Dimethyl-19-nortestosterone 17β-buciclate
    Routes of
    administration    		 Intramuscular injection
    Drug class Androgen; Anabolic steroid; Androgen ester; Progestogen
    Identifiers
    • (1S,2R,9R,10R,11S,14S,15S,17S)-9,15,17-Trimethyl-5-oxotetracyclo[8.7.0.02,7.011,15]heptadec-6-en-14-yl 4-butylcyclohexane-1-carboxylate
    PubChem CID
    Chemical and physical data
    Formula C31H48O3
    Molar mass 468.722 g·mol−1
    3D model (JSmol)
    • [H][C@]12CCC(=O)C=C1C[C@@H](C)[C@H]1[C@@H]3CC[C@H](OC(=O)C4CCC(CCCC)CC4)[C@@]3(C)C[C@H](C)[C@H]21
    • InChI=1S/C31H48O3/c1-5-6-7-21-8-10-22(11-9-21)30(33)34-27-15-14-26-29-19(2)16-23-17-24(32)12-13-25(23)28(29)20(3)18-31(26,27)4/h17,19-22,25-29H,5-16,18H2,1-4H3/t19-,20+,21?,22?,25?,26+,27+,28-,29+,31?/m1/s1
    • Key:SQABEAOHFNPHNY-QFAUYDRKSA-N

    Dimethandrolone buciclate (developmental code name CDB-4386A), or dimethandrolone bucyclate, also known as 7α,11β-dimethyl-19-nortestosterone 17β-buciclate, is a synthetic anabolic–androgenic steroid (AAS) and a derivative of nandrolone (19-nortestosterone) which was developed by the Contraceptive Development Branch (CDB) of the National Institute of Child Health and Human Development (NICHD) and has not been marketed at this time. It is an androgen ester – specifically, the C17β buciclate (4-butylcyclohexane-1-carboxylate) ester of dimethandrolone (7α,11β-dimethyl-19-nortestosterone) – and acts as a prodrug of dimethandrolone in the body. Dimethandrolone buciclate is or was under investigation as a potential male contraceptive.

    See also




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