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Mu-opioid receptor agonists
Doxpicomine
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    Doxpicomine

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    Doxpicomine
    Doxpicomine Structure.svg
    Clinical data
    Routes of
    administration    		 Oral
    ATC code
    • none
    Legal status
    Legal status
    • In general: ℞ (Prescription only)
    Identifiers
    • 1-(1,3-dioxan-5-yl)-N,N-dimethyl-1-pyridin-3-ylmethanamine
    CAS Number
    PubChem CID
    ChemSpider
    UNII
    KEGG
    Chemical and physical data
    Formula C12H18N2O2
    Molar mass 222.288 g·mol−1
    3D model (JSmol)
    • CN(C)C(C1COCOC1)C2=CN=CC=C2
    • InChI=1S/C12H18N2O2/c1-14(2)12(10-4-3-5-13-6-10)11-7-15-9-16-8-11/h3-6,11-12H,7-9H2,1-2H3 ☒N
    • Key:SMZVRZPJXBGNFT-UHFFFAOYSA-N ☒N
     ☒NcheckY (what is this?)  (verify)

    Doxpicomine (Doxpicodin, Doxpizodine) is a mild opioid analgesic drug. The drug acts as a mu-opioid receptor agonist. It is of fairly low potency, with a 400 mg dose of doxpicomine approximately equivalent in pain-killing effect to 8 mg morphine or 100 mg pethidine. It has been used as a lead compound to derive further analogues, although all compounds in this family are comparatively weak mu agonists.


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