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Abandoned drugs
Estradiol butyrylacetate
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    Estradiol butyrylacetate

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    Estradiol butyrylacetate
    Estradiol butyrylacetate.svg
    Clinical data
    Trade names Follikosid, Follikoside, Klimanosid
    Other names EBA; Estradiol 17β-butyrylacetate
    Routes of
    administration    		 Intramuscular injection
    Drug class Estrogen; Estrogen ester
    Identifiers
    • [(8R,9S,13S,14S,17S)-3-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl] 3-oxohexanoate
    CAS Number
    PubChem CID
    ChemSpider
    UNII
    Chemical and physical data
    Formula C24H32O4
    Molar mass 384.516 g·mol−1
    3D model (JSmol)
    • CCCC(=O)CC(=O)O[C@H]1CC[C@H]2[C@@H]3CCc4cc(O)ccc4[C@H]3CC[C@]12C
    • InChI=1S/C24H32O4/c1-3-4-16(25)14-23(27)28-22-10-9-21-20-7-5-15-13-17(26)6-8-18(15)19(20)11-12-24(21,22)2/h6,8,13,19-22,26H,3-5,7,9-12,14H2,1-2H3/t19-,20-,21+,22+,24+/m1/s1
    • Key:LLWMXKOTHFASEO-NTYLBUJVSA-N

    Estradiol butyrylacetate (EBA), sold under the brand names Follikosid and Klimanosid-R Depot (with testosterone ketolaurate and reserpine), is an estrogen medication which is no longer marketed. It is an estrogen ester, specifically, an ester of estradiol. It is administered by intramuscular injection and a single 10 mg dose has been said to have a duration of action of 2 to 3 weeks. The excretion of EBA in women has been studied.

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