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Abandoned drugs
Estradiol furoate
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    Estradiol furoate

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    Not to be confused with Estradiol benzoate or Estrofurate.
    Estradiol furoate
    Estradiol furoate.svg
    Clinical data
    Trade names Di-Folliculine
    Other names EF; 17-Furoylestradiol; 17-(2-Furancarbonyl)estradiol
    Routes of
    administration    		 Intramuscular injection
    Drug class Estrogen; Estrogen ester
    Identifiers
    • [(8R,9S,13S,14S,17S)-3-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl] furan-2-carboxylate
    CAS Number
    PubChem CID
    ChemSpider
    UNII
    Chemical and physical data
    Formula C23H26O4
    Molar mass 366.457 g·mol−1
    3D model (JSmol)
    • C[C@]12CC[C@H]3[C@@H](CCc4cc(O)ccc34)[C@@H]1CC[C@@H]2OC(=O)c5occc5
    • InChI=1S/C23H26O4/c1-23-11-10-17-16-7-5-15(24)13-14(16)4-6-18(17)19(23)8-9-21(23)27-22(25)20-3-2-12-26-20/h2-3,5,7,12-13,17-19,21,24H,4,6,8-11H2,1H3/t17-,18-,19+,21+,23+/m1/s1
    • Key:UZMCMLLMBRERNY-BEARUUAKSA-N

    Estradiol furoate (EF), or estradiol 17β-furoate, sold under the brand name Di-Folliculine, is an estrogen medication and estrogen ester which is no longer marketed. It is the C17β furoate ester of estradiol.Estradiol benzoate has also been marketed under the brand name Di-Folliculine, and should not be confused with estradiol furoate.

    The duration of action of the related estradiol ester estradiol 3-furoate by intramuscular injection was studied in women in 1952. Its duration in oil solution was found to be similar to that of estradiol benzoate in oil solution and shorter than that of estradiol dipropionate in oil solution.

    See also



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