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Haloprogin

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Haloprogin
Haloprogin.svg
Clinical data
Routes of
administration
Topical
ATC code
Legal status
Legal status
  • US: Not available
Identifiers
  • 1,2,4-Trichloro-5-[(3-iodoprop-2-yn-1-yl)oxy]benzene
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard 100.011.169
Chemical and physical data
Formula C9H4Cl3IO
Molar mass 361.38 g·mol−1
3D model (JSmol)
Melting point 113.5 °C (236.3 °F)
Solubility in water Insoluble mg/mL (20 °C)
  • Clc1cc(OCC#CI)c(Cl)cc1Cl
  • InChI=1S/C9H4Cl3IO/c10-6-4-8(12)9(5-7(6)11)14-3-1-2-13/h4-5H,3H2 checkY
  • Key:CTETYYAZBPJBHE-UHFFFAOYSA-N checkY
  (verify)

Haloprogin is an antifungal drug used to treat athlete's foot and other fungal infections. It is marketed in creams under the trade names Halotex, Mycanden, Mycilan, and Polik.

Action

Haloprogin was previously used in 1% topical creams as an antifungal agent. It was marketed over-the-counter primarily to treat tinea infections of the skin. The mechanism of action is unknown.

Haloprogin had a high incidence of side effects including: irritation, burning, vesiculation (blisters), scaling, and itching. It has since been discontinued due to the emergence of more modern antifungals with fewer side effects.


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