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Abandoned drugs
Hexestrol dipropionate
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    Hexestrol dipropionate

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    Hexestrol dipropionate
    Hexestrol dipropionate.svg
    Clinical data
    Other names Hexestrol 4,4'-dipropionate
    Identifiers
    • [4-[4-(4-propanoyloxyphenyl)hexan-3-yl]phenyl] propanoate
    CAS Number
    PubChem CID
    ChemSpider
    UNII
    ChEMBL
    Chemical and physical data
    Formula C24H30O4
    Molar mass 382.500 g·mol−1
    3D model (JSmol)
    • CCC(C1=CC=C(C=C1)OC(=O)CC)C(CC)C2=CC=C(C=C2)OC(=O)CC
    • InChI=1S/C24H30O4/c1-5-21(17-9-13-19(14-10-17)27-23(25)7-3)22(6-2)18-11-15-20(16-12-18)28-24(26)8-4/h9-16,21-22H,5-8H2,1-4H3
    • Key:HZLYMVNJKHJFRO-UHFFFAOYSA-N

    Hexestrol dipropionate (brand name Hexanoestrol, Retalon Oleosum), or hexestrol dipropanoate, is a synthetic, nonsteroidal estrogen of the stilbestrol group related to diethylstilbestrol. It is an ester of hexestrol, and has been known since at least 1931. The drug has been used in the past to inhibit lactation in women.

    Parenteral potencies and durations of nonsteroidal estrogens
    Estrogen Form Major brand name(s) EPD (14 days) Duration
    Diethylstilbestrol (DES) Oil solution Metestrol 20 mg 1 mg ≈ 2–3 days; 3 mg ≈ 3 days
    Diethylstilbestrol dipropionate Oil solution Cyren B 12.5–15 mg 2.5 mg ≈ 5 days
    Aqueous suspension ? 5 mg ? mg = 21–28 days
    Dimestrol (DES dimethyl ether) Oil solution Depot-Cyren, Depot-Oestromon, Retalon Retard 20–40 mg ?
    Fosfestrol (DES diphosphate)a Aqueous solution Honvan ? <1 day
    Dienestrol diacetate Aqueous suspension Farmacyrol-Kristallsuspension 50 mg ?
    Hexestrol dipropionate Oil solution Hormoestrol, Retalon Oleosum 25 mg ?
    Hexestrol diphosphatea Aqueous solution Cytostesin, Pharmestrin, Retalon Aquosum ? Very short
    Note: All by intramuscular injection unless otherwise noted. Footnotes: a = By intravenous injection. Sources: See template.

    See also



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