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Hydroxypethidine
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Hydroxypethidine

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Hydroxypethidine
Hydroxypethidine.svg
Clinical data
ATC code
  • none
Legal status
Legal status
Identifiers
  • Ethyl 4-(3-hydroxyphenyl)-1-methyl-piperidine-4-carboxylate
CAS Number
PubChem CID
ChemSpider
UNII
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard 100.006.738
Chemical and physical data
Formula C15H21NO3
Molar mass 263.337 g·mol−1
3D model (JSmol)
  • O=C(OCC)C2(c1cccc(O)c1)CCN(C)CC2
  • InChI=1S/C15H21NO3/c1-3-19-14(18)15(7-9-16(2)10-8-15)12-5-4-6-13(17)11-12/h4-6,11,17H,3,7-10H2,1-2H3 checkY
  • Key:WTJBNMUWRKPFRS-UHFFFAOYSA-N checkY
  (verify)

Hydroxypethidine (Bemidone) is an opioid analgesic that is an analogue of the more commonly used pethidine (meperidine). Hydroxypethidine is slightly more potent than meperidine as an analgesic, 1.5x meperidine in potency, and it also has NMDA antagonist properties like its close relative ketobemidone.

Hydroxypethidine has similar effects to other opioids, and produces analgesia, sedation and euphoria. Side effects can include itching, nausea and potentially serious respiratory depression which can be life-threatening.

Hydroxypethidine is under international control under the Single Convention on Narcotic Drugs 1961 and therefore controlled like morphine in most countries; in the United States it is a Schedule I Narcotic controlled substance with an ACSCN of 9627 and a 2014 annual aggregate manufacturing quota of 2 grams. The salt in use is the hydrochloride, with a free base conversion ratio of 0.878.

See also



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