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Abandoned drugs
Lapisteride
Другие языки:

    Lapisteride

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    Lapisteride
    Lapisteride.png
    Clinical data
    Routes of
    administration    		 Oral
    ATC code
    • None
    Legal status
    Legal status
    • In general: non-regulated
    Identifiers
    • N-[1-(4-methoxyphenyl)-1-methylethyl]-3-oxo-4-aza-5α-androst-1-ene-17β-carboxamide
    CAS Number
    PubChem CID
    ChemSpider
    UNII
    Chemical and physical data
    Formula C29H40N2O3
    Molar mass 464.650 g·mol−1
    3D model (JSmol)
    • O=C(NC(c1ccc(OC)cc1)(C)C)[C@@H]3[C@]2(CC[C@H]4[C@H]([C@@H]2CC3)CC[C@H]5NC(=O)\C=C/[C@]45C)C
    • InChI=1S/C29H40N2O3/c1-27(2,18-6-8-19(34-5)9-7-18)31-26(33)23-12-11-21-20-10-13-24-29(4,17-15-25(32)30-24)22(20)14-16-28(21,23)3/h6-9,15,17,20-24H,10-14,16H2,1-5H3,(H,30,32)(H,31,33)/t20-,21-,22-,23+,24+,28-,29+/m0/s1 checkY
    • Key:NAGKTIAFDQEFJI-DPMIIFTQSA-N checkY
      (verify)

    Lapisteride (INN; CS-891) is a dual inhibitor of both isoforms of the enzyme 5α-reductase. It was under investigation for the treatment of benign prostatic hyperplasia (BPH) and androgenic alopecia, but was never marketed.

    See also


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