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Hypnotics
ORG-25435
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    ORG-25435

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    ORG-25435
    ORG-25435 Structure.svg
    Identifiers
    • (2,6-dimethoxy-4-methylphenyl)-(2R)-2-[bis(2-methoxyethyl)amino]butanoate
    CAS Number
    PubChem CID
    UNII
    Chemical and physical data
    Formula C19H31NO6
    Molar mass 369.458 g·mol−1
    3D model (JSmol)
    • COc1cc(C)cc(OC)c1OC(=O)C(CC)N(CCOC)CCOC

    ORG-25435 is a synthetic drug developed by Organon International, which acts as a GABAA receptor positive allosteric modulator, and produces sedative effects. It has been researched for use as an intravenous anesthetic agent, with positive results in initial trials, although negative side effects like hypotension and tachycardia, as well as unpredictable pharmacokinetics at higher doses, have meant it has ultimately not been adopted for medical use.


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