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Phenaridine
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Phenaridine

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Phenaridine
Phenaridine.svg
Phenaridine 3D BS.png
Clinical data
ATC code
  • none
Legal status
Legal status
Identifiers
  • N-[2,5-Dimethyl-1-(2-phenylethyl)piperidin-4-yl]-N-phenylpropanamide
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
Formula C24H32N2O
Molar mass 364.533 g·mol−1
3D model (JSmol)
  • O=C(N(c1ccccc1)C3CC(N(CCc2ccccc2)CC3C)C)CC
  • InChI=1S/C24H32N2O/c1-4-24(27)26(22-13-9-6-10-14-22)23-17-20(3)25(18-19(23)2)16-15-21-11-7-5-8-12-21/h5-14,19-20,23H,4,15-18H2,1-3H3 checkY
  • Key:ODPKHHGQKIYCTJ-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Phenaridine (2,5-dimethylfentanyl) is an opioid analgesic that is an analogue of fentanyl. It was developed in 1972, and is used for surgical anasthesia.

Phenaridine has similar effects to fentanyl. It is slightly less potent than fentanyl in rats. Side effects of fentanyl analogs are similar to those of fentanyl itself, which include itching, nausea and potentially serious respiratory depression, which can be life-threatening. Irresponsible use of fentanyl analogues administrated in several times larger doses than recommended, have ended up in a death of hundreds of people throughout Europe and the former Soviet republics since the most recent resurgence in use began in Estonia in the early 2000s, and novel derivatives continue to appear.

See also


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