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Mu-opioid receptor agonists
Propylketobemidone
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    Propylketobemidone

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    Propylketobemidone
    Propylketobemidone.svg
    Clinical data
    ATC code
    • none
    Identifiers
    • 1-[4-(3-hydroxyphenyl)-1-methylpiperidin-4-yl]butan-1-one
    CAS Number
    PubChem CID
    ChemSpider
    UNII
    Chemical and physical data
    Formula C16H23NO2
    Molar mass 261.365 g·mol−1
    3D model (JSmol)
    • O=C(CCC)C1(CCN(C)CC1)c2cccc(O)c2
    • InChI=1S/C16H23NO2/c1-3-5-15(19)16(8-10-17(2)11-9-16)13-6-4-7-14(18)12-13/h4,6-7,12,18H,3,5,8-11H2,1-2H3 checkY
    • Key:VQISXVAQCJSTNS-UHFFFAOYSA-N checkY
      (verify)

    Propylketobemidone is an opioid analgesic that is an analogue of ketobemidone. It was developed in the 1950s during research into analogues of pethidine and was assessed by the United Nations Office on Drugs and Crime but was not included on the list of drugs under international control, probably because it was not used in medicine or widely available.

    Propylketobemidone is so named because it is the propyl ketone analogue of bemidone (hydroxypethidine). The more commonly used ethyl ketone ("ethylketobemidone") is simply called ketobemidone, as it is the only drug of this family to have been marketed.

    Presumably propylketobemidone produces similar effects to ketobemidone and other opioids, such as analgesia and sedation, along with side effects such as nausea, itching, vomiting and respiratory depression which may be harmful or fatal.




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