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Abandoned drugs
Sturamustine
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    Sturamustine

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    Sturamustine
    Sturamustine.svg
    Clinical data
    Other names Dehydroepiandrosterone (DHEA) 17β-N-(2-chloroethyl)-N-nitrosourea; N-(2-Chloroethyl)-N'-(3-hydroxyandrost-5-en-17-yl)-N-nitrosourea
    Identifiers
    • N-(2-chloroethyl)-N'-[(3β,17β)-3-hydroxyandrost-5-en-17-yl]-N-nitrosocarbamimidic acid
    CAS Number
    ChemSpider
    Chemical and physical data
    Formula C22H34ClN3O3
    Molar mass 423.98 g·mol−1
    3D model (JSmol)
    • C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2/N=C(/N(CCCl)N=O)\O)CC=C4[C@@]3(CC[C@@H](C4)O)C
    • InChI=1S/C22H34ClN3O3/c1-21-9-7-15(27)13-14(21)3-4-16-17-5-6-19(22(17,2)10-8-18(16)21)24-20(28)26(25-29)12-11-23/h3,15-19,27H,4-13H2,1-2H3,(H,24,28)/t15-,16-,17-,18-,19-,21-,22-/m0/s1
    • Key:QSHCCJGNLACWQQ-UMWWKMARSA-N

    Sturamustine, also known as dehydroepiandrosterone (DHEA) 17β-N-(2-chloroethyl)-N-nitrosourea, is a synthetic androstane steroid and a C17β nitrosourea conjugate of dehydroepiandrosterone (DHEA) which was developed as a cytostatic antineoplastic agent (i.e., a chemotherapy drug) for the treatment of hormone-dependent tumors but was never marketed. It was synthesized in 1982.

    See also


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