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Abandoned drugs
Topterone
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Topterone

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Topterone
Topterone.svg
Clinical data
Other names WIN-17665; Propyltestosterone; 17α-Propyltestosterone; 17α-Propylandrost-4-en-17β-ol-3-one
Routes of
administration		 Topical
Identifiers
  • (8R,9S,10R,13S,14S,17S)-17-hydroxy-10,13-dimethyl-17-propyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
ECHA InfoCard 100.056.638
Chemical and physical data
Formula C22H34O2
Molar mass 330.512 g·mol−1
3D model (JSmol)
  • CCCC1(CCC2C1(CCC3C2CCC4=CC(=O)CCC34C)C)O
  • InChI=1S/C22H34O2/c1-4-10-22(24)13-9-19-17-6-5-15-14-16(23)7-11-20(15,2)18(17)8-12-21(19,22)3/h14,17-19,24H,4-13H2,1-3H3/t17-,18+,19+,20+,21+,22+/m1/s1
  • Key:LZSOOHLAZHOTHJ-GUCLMQHLSA-N

Topterone (INN, USAN) (developmental code name WIN-17665), also known as 17α-propyltestosterone (or simply propyltestosterone) or as 17α-propylandrost-4-en-17β-ol-3-one, is a steroidal antiandrogen that was first reported in 1978 and was developed for topical administration but, due to poor effectiveness, was never marketed.

See also




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