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Abandoned drugs
Trendione
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    Trendione

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    Trendione
    Trendione.svg
    Clinical data
    Other names RU-2065; Trenavar; Triendione; Estra-4,9,11-triene-3,17-dione
    Drug class Androgen; Anabolic steroid; Progestogen
    Identifiers
    • (8S,13S,14S)-13-Methyl-1,2,6,7,8,14,15,16-octahydrocyclopenta[a]phenanthrene-3,17-dione
    CAS Number
    PubChem CID
    ChemSpider
    UNII
    CompTox Dashboard (EPA)
    Chemical and physical data
    Formula C18H20O2
    Molar mass 268.356 g·mol−1
    3D model (JSmol)
    • C[C@]12C=CC3=C4CCC(=O)C=C4CC[C@H]3[C@@H]1CCC2=O
    • InChI=1S/C18H20O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h8-10,15-16H,2-7H2,1H3/t15-,16+,18+/m1/s1
    • Key:KBSXJBBFQODDTQ-RYRKJORJSA-N

    Trendione (developmental code name RU-2065; nickname Trenavar), also known as estra-4,9,11-triene-3,17-dione, is an androgen prohormone as well as metabolite of the anabolic steroid trenbolone. Trendione is to trenbolone as androstenedione is to testosterone. The compound is inactive itself, showing more than 100-fold lower affinity for the androgen and progesterone receptors than trenbolone. It is a designer steroid and has been sold on the internet as a "nutritional supplement". Trendione is listed in the United States Designer Anabolic Steroid Control Act of 2014.

    See also




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