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ZM-182345
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    ZM-182345

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    ZM-182345
    ZM-182345.svg
    Identifiers
    • 2-Hydroxy-N-[4-nitro-3-(trifluoromethyl)phenyl]-4-phenyl-2-(trifluoromethyl)pentanamide
    PubChem CID
    Chemical and physical data
    Formula C19H16F6N2O4
    Molar mass 450.337 g·mol−1
    3D model (JSmol)
    • CC(CC(C(=O)NC1=CC(=C(C=C1)[N+](=O)[O-])C(F)(F)F)(C(F)(F)F)O)C2=CC=CC=C2
    • InChI=1S/C19H16F6N2O4/c1-11(12-5-3-2-4-6-12)10-17(29,19(23,24)25)16(28)26-13-7-8-15(27(30)31)14(9-13)18(20,21)22/h2-9,11,29H,10H2,1H3,(H,26,28)
    • Key:RETGATTXHQWSOT-UHFFFAOYSA-N

    ZM-182345 is a nonsteroidal progestin that was never marketed. It was derived from structural modification of the nonsteroidal antiandrogen hydroxyflutamide. ZM-182345 was found to be at least as potent as progesterone as a progestogen in animals but to also possess androgenic activity.




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