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Atypical antipsychotic
Olanzapine/samidorphan
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    Olanzapine/samidorphan

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    Olanzapine/samidorphan
    Combination of
    Olanzapine Atypical antipsychotic
    Samidorphan Opioid antagonist
    Clinical data
    Trade names Lybalvi
    Other names ALKS-3831; OLZ/SAM
    AHFS/Drugs.com Micromedex Detailed Consumer Information
    MedlinePlus a621051
    License data
    Routes of
    administration    		 By mouth
    ATC code
    Legal status
    Legal status
    Identifiers
    KEGG

    Olanzapine/samidorphan, sold under the brand name Lybalvi, is a fixed-dose combination medication for the treatment of schizophrenia and bipolar I disorder. It contains olanzapine, an atypical antipsychotic, and samidorphan, an opioid antagonist. Samidorphan reduces the weight gain associated with olanzapine while still allowing olanzapine to exert its therapeutic effect. The formulation was approved for medical use in the United States in May 2021.

    [[[Category:Serotonin receptor antagonists]]



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